Smell, Stress, and Synapses: Four Ways the Nose Tells Us More Than we Realize

Smell is often written off as a minor sense – but biologically, it’s a direct and highly sensitive portal into the nervous system.

In this new instalment of our Senses series, we look at four recent studies that show how olfaction flags early neuroinflammation through A1R upregulation, adapts to mechanical stress via CNGA2-positive neurons, responds to chemical cooling through TRPM8, and encodes memory with shifting GluN2A/GluN2B NMDA receptor composition.

The nose is doing more than detecting chemicals. It’s telling the brain how the body is doing.

Read more https://www.alomone.com/smell-under-pressure-what-the-nose-reveals-about-the-brain

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