Your Synaptic Markers Guide: Pre- and Postsynaptic Region

ALOMONE LABS NEWS

If you're trying to label synapses without performing electron microscopy, antibody-based detection is still your best option. However, sorting through presynaptic vs. postsynaptic markers can be time-consuming.

We’ve assembled a list of 17 well-tested markers – covering everything from presynaptic markers such as SNAP-25, VGLUTs, and synaptophysin to postsynaptic proteins including PSD95, neuroligins, and Shank proteins – all tested in-house.

The guide includes:

Clear demarcation of presynaptic vs. postsynaptic regions

Protocol notes for IHC, ICC, WB, and multiplex assays

Tips on tissue penetration, fluorophore conjugates, and clearing

Whether you’re setting up new workflows or confirming your marker set, this resource provides practical, ready-to-use guidance.

Discover more https://www.alomone.com/synaptic-markers-for-pre-and-postsynaptic-regions

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