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Cell Surface-Binding Antibodies Part 1: Target the Surface, Stay Out of the Cell

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Ion channels aren’t the static entities we often think of them as – they translocate, cluster, internalize, and reset. But you’ll miss it all if your antibody only works after fixation. In this blog we show you how cell surface-binding antibodies reveal the dynamics of TRPV1 trafficking in live neurons – using a live-cell ICC approach validated in real experiments. This is Part 1 in our 4-part series on what these antibodies let you do.


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