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Cell Surface-Binding Antibodies Part 3: Tracking Live Receptors with Quantum Dots

ALOMONE LABS NEWS


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Following NMDA receptor subtypes in live neurons


NMDA receptors are crucial for how neurons learn and adapt. They’re also complex beasts – built from multiple subunits, moving constantly across the neuronal membrane and changing roles as the brain develops.


To understand that behavior, you need to see what each subunit does. Not in fixed slices. Not averaged over a population. But in real time, on the surface of living cells. That’s exactly what researchers have been doing with a combination of cell surface-binding antibodies and quantum dots.


This is the third blog in a series on how cell surface-binding antibodies open up powerful experimental possibilities. And now we’re looking a little deeper, because to know what surface proteins do, you have to be able to watch them.



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