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Neural Stem Cells Found Outside the Brain

ALOMONE LABS NEWS


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A new study in Nature Cell Biology revealed that neural stem cells (NSCs) aren’t limited to the brain and spinal cord. Researchers identified multipotent peripheral NSCs (pNSCs) in the lung, tail, and dorsal root ganglia that self-renew, express canonical markers, and differentiate into neurons and glia – without reprogramming.


Remarkably, these neurons are electrically active, showing voltage-gated sodium and potassium currents, with the sodium current fully blocked by Tetrodotoxin citrate (TTX, #T-550).


If similar cells exist in humans, pNSCs could redefine neural repair and impact the future of neuron-based therapies.


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Neural Stem Cells Found Outside the Brain

A Nature Cell Biology study found multipotent peripheral neural stem cells beyond the CNS. They form active neurons, blocked by TTX, hinting at new paths for neural repair and therapy.



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