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New Synthetic Ant Toxins for NaV Channel Research

ALOMONE LABS NEWS


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Voltage-gated sodium (NaV) channels are central to sensory signalling – and a growing target for non-opioid pain therapies. NaV1.8, for example, is now being clinically targeted with subtype-selective inhibitors like Suzetrigine (VX‑548), recently FDA-approved for acute pain. But just as silencing these channels informs treatment, activating or modulating them with accuracy lets you dissect their native function in live systems.


To support this, we’ve added five synthetic ant toxins to our NaV channel modulator portfolio:

Ectatotoxin-Rm4a (#STR-010)

Myrmicitoxin-Pm1a (#STP-030)

Myrmicitoxin-Pm2a (#STP-040)

Ta3a (#STT-020)

Poneratoxin (#STP-360)

Each targets specific NaV subtypes with defined biophysical effects.

Safety is built in.

We know “toxin” can sound alarming. But in a controlled lab, it’s just another tool, and one we take seriously. Every Alomone Labs peptide toxin is shipped with a full EC-compliant Safety Data Sheet (SDS) and handling guidelines. Follow standard protocols and you’ll find these reagents are safe, stable, and reliable to work with. No extra precautions needed – just proper lab practice.

All five peptides are now available in synthetic form – made and tested in-house.


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